Friedrich Lab
Biomolecular NMR Spectroscopy
The Friedrich Lab at the University of Cologne uses NMR to uncover structure–activity relationships in biomolecules and establish molecular principles of biological function.
Our research focuses on how dynamic transitions mediated by biomolecular interactions govern biological function at atomic resolution, particularly in antimicrobial peptides and RNA-mediated processes. By identifying generalizable molecular design principles, we aim to enable the rational development of functional biomolecules.
Picture: Barth van Rossum
The Group | Front: Benno, Lena, Sonja, Franka, Daniel | Back: Annika, Matilde, Kathrin, Daniela, Philipp
Photo: Sarah Hensel
Our recent key findings establish structure–activity relationships in antimicrobial peptides
1. Quagliata et al. 2025, https://doi.org/10.1021/acs.biochem.5c00101
2. Quagliata et al. 2026, https://doi.org/10.1016/j.ejmech.2026.119122
Dr. Daniel Friedrich
Biomolecular NMR Spectroscopy and NMR Facility
Department of Chemistry and Biochemistry
University of Cologne
Greinstraße 4
50939 Cologne, Germany
Room 114 (Organic Chemistry Building)
Phone +49 221 470 3081
Email daniel.friedrich[at]uni-koeln.de